Effect of Ketamine on LTP and NMDAR EPSC in Hippocampus of the Chronic Social Defeat Stress Mice Model of Depression

Depression is a common mental disorder that is associated with memory dysfunction.Ketamine has recently been demonstrated to be a rapid antidepressant.The mechanisms underlying how depression induces memory dysfunction and how ketamine relieves depressive symptoms remain poorly understood.This work compared three groups of male C57BL/6J mice: mice

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